Clinical Signs:
- Enlargement of superficial lymph nodes
- Weakness and depression
- Anorexia and vomiting
- Thirst and polyuria
- Dyspnoea and coughing
- Ocular and nasal discharge
- Unilateral or bilateral bulging of eyes
- Jaundice and ascites
- Anemia
- Tendency to bleed easily or nose bleeding
- Chronic leukaemia as progress slowly donot show any typical signs. They are picked up at routine veterinary examinations or during investigation for something completely unrelated.
- Fall of milk yield in cattle
- Abomasal ulceration and haemorrhage
- Enlarged thymus or thoracic lymph nodes
- Posterior paresis
Diagnosis:
- Based on clinical findings
- Blood examination; CBC, blood smear examination
- Bone marrow examination
Treatment:
- No specific treatment is available to this disease. Treatment principles for this disease is to expand life of animal and improve life quality of affected animals.
- Supportive care should be given such as fluid therapy to replenish fluid lost, administering antibiotics, supplementing animal’s body with blood components and feeding them well-balanced and healthy diet.
- Chemotherapy or immunotherapy or combination of both. Drugs like prednisolone, methotrexate, chlorambucicyclophosphamide has found to be effective. These medicine are usually given in oral form and in severe cases parenteral injection is given.
- Repeated blood transfusion is required.