Leucopenia:
- Leucopenia doesnot occurs as specific disease but occurs as manifestation of variety of disease.
- Leucopenia refers to decreased in number of WBC or leukocytes in circulation.
- Neutropenia often accompanied with lymphopenia occurs in number of acute viral disease like hog cholera, equine viral arteritis.
- Acute local inflammation causes transient fall in leukocytes because of withdrawal of circulating cells to septic focus.
- Neutropenia occurs as a part of response to toxaemia and endotoxaemia. Lymphopenia occurs as part of stress response, and as a result of administration of glucocorticoids.
Etiology:
- Canine distemper
- Infectious canine hepatitis
- Feline panleukopenia
- Swine fever, bovine viral diarrhoea
- Rinderpest, toxoplasmosis
- Shock
- Bone marrow hypoplasia
- Chronic nephritis
- Administration of drugs like chloramphenicol, streptomycin, Griesofulvin
- Ingestion of metals; arsenic, lead, mercury, thallium