Ways to Reduce Bacterial Resistance/ Successful Antimicrobial Therapy:
- Narrow spectrum drug should be recommended first. Broad spectrum drugs should be reserved for situation where it is specific or where causative agent is not known.
- Bactericidal should be preferred over bacteriostatic
- Less toxic antimicrobial should be used than potentially more toxic agent.
- Antimicrobial that requires less frequent administration should be preferred than that which is given after short intervals.
- For less severe infection, oral antimicrobial drug should be used but for severe infection parenteral antimicrobial drug should be used.
- Antimicrobial agent should always be use in proper dose and for proper duration of time.
- Antimicrobial therapy should only be used when medical indications are clear
- Overuse of newer agents should be avoided when already available agents are effective.
- Less expensive drugs should be preferred and drug should that are easily available
- Antimicrobial drug should not be used to treat trivial, self-limiting or untreatable infections.