Course Content
History of genetics
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Extra-nuclear inheritance – genes in organelles, maternal effect, criteria for extra-nuclear inheritance
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Mutation – genic, chromosomal and molecular levels
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Learn Introductory Genetics with Rahul

Recombination

  • Recombination is a process by which pieces of DNA are broken and recombined to produce new combinations of alleles.
  • Crossovers result in recombination and the exchange of genetic material between the maternal and paternal chromosomes.
  • As a result, offspring can have different combinations of genes than their parents.

Homologous Recombination in Eukaryotes, Bacteria and Viruses

Coefficient of coincidence

  • In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis.
  • It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. This is called interference.

 

 

Linkage Map

  • A linkage map (also known as a genetic map) is a table for a species or experimental population that shows the position of its known genes or genetic markers relative to each other in terms of recombination frequency, rather than a specific physical distance along each chromosome.
  • Genetic linkage map, also known as genetic map, is a linear graph of the sequence and relative distance of molecular markers on chromosome based on the frequencies of recombination between markers during crossover of homologous chromosomes.

 

Map Unit

  • In genetics, a centimorgan (abbreviated cM) or map unit (m.u.) is a unit for measuring genetic linkage.
  • It is defined as the distance between chromosome positions (also termed loci or markers) for which the expected average number of intervening chromosomal crossovers in a single generation is 0.01.

 

Three-point cross

  • In genetics, a three-point cross is used to determine the loci of three genes in an organism’s genome.
  • If the recombination frequency is greater than 50 percent, it means that the genes are unlinked – they are either located on different chromosomes or are sufficiently distant from each other on the same chromosome.

 

Two-point cross

  • It is a cross in which two genes participate.
  • So, a cross between a dihybrid and a double recessive homozygous individual is known as two-point cross.
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