Ethical Guidelines for the Use of Animals in Research (National Committee for Research Ethics in Science and Technology (NENT), 2018)

1. Respect for animals’ dignity
2. Responsibility for considering options (Replace)
3. The principle of proportionality: responsibility for considering and balancing suffering and benefit
4. Responsibility for considering reducing the number of animals (Reduce)
5. Responsibility for minimising the risk of suffering and improving animal welfare (Refine)
6. Responsibility for maintaining biological diversity
7. Responsibility when intervening in a habitat
8. Responsibility for openness and sharing of data and material
9. Requirement of expertise on animals
10. Requirement of due care