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Master Animal Ethics and Welfare – Notes, Case Studies and Practical Insights – with Rahul

Refining endpoints

  • The majority of animals are killed at the end of the experiment, either because their tissues are required as part of the experiment, or because the scientific objectives have been achieved and the animal can no longer be used
  • If the experiment leads to an increasing amount of suffering during its course then it is best for the animals to be killed as early as possible.
  • This approach is described as operating ‘humane endpoints’
  • Setting the earliest possible endpoint for the experiment. That is, if the necessary information can be gathered before the animal experiences any ill effects from the experiment, this should be defined as the endpoint and the animal subsequently euthanized.
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