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Biochemistry and molecular logic of life
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Master General Biochemistry – Notes, Case Studies & Practical Insights – with Rahul

Haemoglobin buffer system

  • Inside the erythrocyte, CO2 combines with water to form H2CO3 under the action of carbonic anhydrase enzyme.

 

HbO2 ⇌ Hb + O2 —i)

Hb + H2CO3 ⇌ HHb + HCO3 – ii)

HHB + O2 ⇌ HHbO2

HHbO2 ⇌ HbO2  + H +

HCO3 + H+  ⇌ H2CO3

H2CO3  ⇌ H2O + CO2  

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