Lipoproteins (Lipids + Proteins)

• Globular micelle-like particles.
• Consists of non-polar core of triglycerols and cholestroyl esters,
• Protein part of lipoprotein is called apolipoprotein and acts as cellular targeting signals.

Classes of lipoprotein

a) Chylomicrons:

• Transport dietry glyceride and cholesterol from intestine to tissue.

b) VLDL:

• Transport glyceride from liver to tissue.

c) LDL:

• Delivers cholesterol to the cells.

d) IDL:

• Pickup cholesterol from HDL to become LDL.

e) HDL:

• Delivers cholesterol to liver.

Note:

• Intestinal mucosal cells convert dietary FA to triacylglycerol and package them.
• Particles are released to intestinal lymph.
• Transported through lymphatic vessels.
• Blood stream then delivers chylomicrons throughout the body.