Pancreatic Juice:

Composition:

• enzymes(Trypsinogen, chymotrypsinogen, carboxypeptidase, trypsin, amylase, lipase)
• Alkaline fluid

Function

• Breakdown of carbohydrate, protein, fat; thus help in digestive function
• It is alkaline in nature thus neutralize HCl from chyme entering the duodenum.
• It releases insulin and glucagon. Excess glucose is converted into glycerol.

Regulation

• Pancreatic juice is produced in pancreas.
• Acinar cell of pancreas synthesize and secrets fluids into duct.
• This fluid gets modified and drop in duodenum.
• When acidic chyme is entered into duodenum, that fluid get stimulated. That fluid is hormone i.e. secretin and cholecystokinin.
• This pancreatic juice is alkaline in nature as it contains bicarbonate.
• Pancreatic enzymes are originated from acinal cells and bicarbonate from duct cells.
• bicarbonate: neutralize the acidic chyme
• Enzyme: Breakdown carbohydrate, protein, fat.